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Fasoracetam – Powder, 1 gram

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Fasoracetam (NS-105) is a racetam-class compound with a mechanistic profile distinct from piracetam — it functions as a group II metabotropic glutamate receptor (mGluR2/3) agonist and upregulates functional GABA-B receptor expression. These mechanisms distinguish fasoracetam from AMPA-modulating racetams and from direct GABA-B agonists (phenibut, baclofen). Research applications include mGluR2/3 pharmacology, GABA-B receptor expression regulation, and comparative racetam mechanism studies.

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3D Molecular Structure

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Chemical Formula C10H16N2O2
Synonyms Fasoracetam 110958-19-5 Fasoracetam [INN] N-(5-Oxo-D-prolyl)piperidine NS 105
Molar Mass 196.25 g/mol
CAS Number 110958-19-5
PubChem CID 198695
Total Compound Content 1 g powder
Shelf Life 36 months
Fasoracetam ((5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one) is a racetam-class compound characterized by a pharmacological profile distinct from many other members of the racetam family. Experimental investigations have examined its interactions with group II metabotropic glutamate receptors (mGluR2 and mGluR3), GABA-B receptor-associated signaling systems, and high-affinity choline transport mechanisms. Through these pathways, fasoracetam has been utilized in studies of receptor-mediated signal transduction, neurotransmitter-associated regulatory networks, intracellular communication pathways, and molecular mechanisms governing synaptic signaling. The powder format provides flexibility for formulation development, analytical chemistry applications, concentration-response investigations, and experimental designs requiring precise control over preparation parameters. Independently third-party HPLC-tested; COA available per batch.

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How does fasoracetam's mechanism differ from other racetam compounds?

Fasoracetam is distinguished by its interactions with group II metabotropic glutamate receptors (mGluR2 and mGluR3), GABA-B receptor-associated signaling systems, and high-affinity choline transport mechanisms. While other racetam compounds have been investigated primarily in relation to ionotropic glutamate receptor modulation, fasoracetam provides a useful research tool for studying metabotropic receptor pharmacology, receptor-mediated signal transduction, and neurotransmitter-associated regulatory networks. This distinct interaction profile makes it valuable for comparative investigations within the racetam class.

What makes fasoracetam useful for mGluR-related research?

Fasoracetam has been widely investigated in studies involving group II metabotropic glutamate receptor signaling, receptor activation mechanisms, and downstream regulatory pathways. Experimental research has examined its interactions with mGluR-associated signaling networks, intracellular communication systems, and molecular processes involved in receptor-mediated regulation. These characteristics make fasoracetam a useful tool for investigating mGluR pharmacology and comparative receptor signaling mechanisms.

How does fasoracetam interact with GABA-B receptor-associated pathways?

Experimental investigations have examined fasoracetam's relationship with GABA-B receptor-associated signaling systems and regulatory mechanisms governing receptor function. Unlike compounds studied primarily for direct receptor interactions, fasoracetam has been utilized in research exploring receptor regulation, signaling pathway modulation, and molecular processes associated with GABA-B-mediated communication networks. This profile makes it valuable for mechanistic studies of receptor-associated signaling and neurotransmitter regulatory systems.

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