5-amino-1MQ is a derivative of methylquinolinium (MQ) that has high efficacy in inhibiting the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). NNMT is a compound linked to cancer, metabolic disorders, and degeneration of brain cells. It also plays a significant role in metabolism and energy and is predominantly active in fat tissue.
By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1), aka the longevity gene, suggesting its essential role in anti-aging.
Research has suggested that activating SIRT1 may have therapeutic potential for various conditions, including metabolic disorders, neurodegenerative diseases, and cancer.
Methylene Blue is potentially one of the most important anti-aging and neurological disease-preventing nootropics available today because of its ability to quickly cross the blood-brain barrier.
It works by enhancing mitochondrial efficiency and respiration, acting as an antioxidant, and increasing brain cell lifespan, all resulting in better mitochondrial function. Originally used to treat malaria, it is currently being studied as a potential therapy for mild cognitive impairment, Alzheimer’s, Parkinson’s disease, and other neurodegenerative disorders.
Shelf Life: 36 months
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