Tadalafil, which is more commonly known under the marketed brand name “Cialis” is a substance recognized for curing male sexual function issues such as erectile dysfunction. It works by stimulating the flow of blood to the penis, thus allowing the individual to have an erection for longer. However, that is not all. It is also used to provide relief to the symptoms of BPH (Benign Prostatic Hyperplasia) also referred to as an enlarged prostate. It helps give relief to symptoms such as frequent urination. It functions by relaxing and smoothing out the muscles in the prostate and in the bladder. Another key role of Tadalafil (Cialis) pills is its ability to help in managing pulmonary arterial hypertension.
Like Sildenafil and Vardenafil, Tadalafil is suggested as a ‘case by case’ medicine. Cialis is also offered as a once-daily dosage.
Tadalafil is an annulated 2,5-diketopiperazine. It is also a 1,2,3,4-tetrahydro-β-carboline.
Tadalafil can be integrated beginning from (D)- tryptophan methyl ester and piperonal by means of a Pictet–Spengler response, followed by condensation with chloroacetyl chloride and methylamine, completing the diketopiperazine ring:
Other Names: 351, IC, Cialis, IC 351, IC-351, IC351
Total Amount of Active Ingredient: 1200 mg
Concentration: 20 mg
Quantity: 60 capsules
Shelf Life: 36 months
Packaging: bottle
What is Tadalafil?
Tadalafil is a prescription medication. It is available as an oral tablet. Tadalafil oral tablets are marketed under the brand names Cialis and Adcirca. There is also a generic version available. Generic drugs are typically less expensive than brand-name drugs. They may not be available in all strengths or forms as the brand-name drug in some cases.
Benefits and Uses
- Tadalafil belongs to a class of drugs known as phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation to treat erectile dysfunction.
- An erection can result from increased blood flow. Tadalafil works to treat PAH by relaxing blood vessels in the lungs, allowing blood to flow more freely.
Additional Information on Tadalafil
Increased penile blood flow caused by relaxation of penile arteries and corpus cavernosal smooth muscle causes penile erection during sexual stimulation. The release of nitric oxide (NO) from nerve terminals and endothelial cells stimulates the synthesis of cGMP in smooth muscle cells, resulting in this response. Smooth muscle relaxation and increased blood flow into the corpus cavernosum are caused by cyclic GMP. By increasing the amount of cGMP, phosphodiesterase type 5 (PDE5) inhibition improves erectile function.
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