Product Usage: This product is intended for research purposes only.
All product information available on this website is for educational purposes only. Any form of bodily introduction into humans or animals is strictly prohibited by law. This product should only be handled by licensed and qualified professionals. It is not a drug, food, or cosmetic, and must not be misbranded, misused, or mislabeled as such.
Pancragen, 20mg
NOTE: In some cases wherein the assigned top colors are out of stock, a different top color will be used to ensure that your order will not be delayed.
Peptides are stable at room temperature and can be stored in their original packaging for several days to weeks. For longer storage, keep them at 4 °C or colder, away from intense light. Do not shake peptides before or after reconstitution, refrigerate them, and handle with care.
You can purchase BAC water here:
BAC 10ml
During our packaging transition, you may receive products with either our previous or updated label. Rest assured, the formulation, purity and quality remain exactly same as standards.
Pancragen is a synthetic tetrapeptide bioregulator studied for its activity in pancreatic tissue models. Research interest centers on its proposed influence on endocrine signalling pathways, including those related to glucose metabolism and melatonin regulation. Research applications include pancreatic endocrine pathway studies, glucose metabolism research, and comparative bioregulatory tetrapeptide pharmacology.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
| Chemical Formula | C26H36N6O9 |
|---|---|
| Synonyms | SCHEMBL5491754 |
| Molar Mass | 576.25 g/mol |
| Total Compound Content | 20mg per vial |
| Shelf Life | 36 months |
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
What pancreatic islet cell models are used to study Pancragen's effects on glucose metabolism pathways
Isolated pancreatic islet cell cultures and beta-cell-derived cell lines are standard models for studying Pancragen's effects on glucose-stimulated insulin secretion, typically measuring insulin release in response to standard glucose challenge with and without Pancragen pre-treatment or co-treatment. Rodent models of induced diabetes (such as streptozotocin-induced models) provide a complementary in vivo system for studying Pancragen's effects on blood glucose regulation and pancreatic tissue endpoints within an intact metabolic system.
How is Pancragen's proposed effect on pancreatic differentiation transcription factors investigated?
Pancreatic progenitor or islet cell models are used to measure expression of key differentiation transcription factors (such as Ptf1a, Pdx1, Pax6, Foxa2, Nkx2.2, and Pax4) by qPCR or immunostaining following Pancragen exposure, allowing researchers to characterise whether the peptide influences the transcriptional program governing pancreatic cell maturation and identity. These molecular endpoints are often paired with functional assays (such as insulin secretion capacity) to connect transcriptional changes to downstream functional outcomes.
What aging-related metabolic models are used to study Pancragen's relevance to age-associated endocrine changes?
Aged rodent models, sometimes studied across multiple age cohorts, are used to examine Pancragen's effects on metabolic biomarkers associated with aging, including measures of cellular senescence and stress-response markers alongside standard metabolic endpoints (blood glucose, insulin sensitivity indices). Comparative analysis across young versus aged model cohorts allows researchers to determine whether Pancragen's effects on these endpoints are age-dependent, which is relevant to broader bioregulatory peptide research examining age-related applications across multiple organ systems.
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