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Product Usage: This product is intended for research purposes only.

All product information available on this website is for educational purposes only. Any form of bodily introduction into humans or animals is strictly prohibited by law. This product should only be handled by licensed and qualified professionals. It is not a drug, food, or cosmetic, and must not be misbranded, misused, or mislabeled as such.

TB-500 (0.5mg/capsule), 60 Capsules

SKU:TB500-60C
Quantity
$149.99
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TB-500 (Thymosin Beta-4) capsules provide an oral administration format for the 7-amino-acid fragment of Thymosin Beta-4 containing the LKKTET actin-binding motif, enabling oral route investigations alongside the lyophilized vial format. As with the injectable format, the active compound interacts with G-actin through its LKKTET motif, influencing actin polymerization dynamics, cytoskeletal organization, and cell migration–associated signaling pathways. Experimental investigations have examined TB-500 in relation to actin-regulatory mechanisms, molecular signaling networks, and pathway-specific processes involved in cytoskeletal biology. Research applications include oral versus parenteral comparative studies, actin cytoskeletal pathway investigation, cell migration signaling research, and mechanistic evaluation of actin-associated regulatory systems.

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3D Molecular Structure

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Chemical Formula C38H68N10O14
Synonyms TB-500, Ac-LKKTETQ, Thymosin Beta-4 fragment (17-23)
Molar Mass 889.01 g/mol
CAS Number 885340-08-9
PubChem CID 62707662
Total Compound Content 30 mg (0.5 mg per capsule)
Shelf Life 36 months
TB-500 (Thymosin Beta-4 analogue) capsules (0.5 mg/capsule) provide an oral administration format for the 7-amino-acid fragment of Thymosin Beta-4 containing the LKKTET actin-binding motif. The primary characterized mechanism—LKKTET motif-mediated interaction with G-actin—is identical to the injectable vial format. The capsule format enables investigation of alternative administration routes and provides a useful platform for studies examining compound transport, peptide stability, and route-dependent signaling characteristics. Experimental research has examined TB-500 in relation to actin polymerization dynamics, cytoskeletal organization, cell migration-associated pathways, and molecular signaling networks linked to actin-regulatory systems. The oral format is also useful for studies requiring non-parenteral delivery approaches or investigations of peptide-associated signaling processes across distinct experimental environments. Independently third-party HPLC-tested; COA available per batch.

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What is the research basis for the TB-500 capsule format?

TB-500 capsules provide an oral format for the Ac-LKKTETQ fragment of Thymosin Beta-4, the region containing the LKKTET actin-binding motif. Experimental studies have examined formulation-dependent characteristics, peptide stability properties, compound-processing mechanisms, and actin-associated signaling pathways.

What is the difference between TB-500 capsules and TB-500 vials for laboratory research?

They contain different compounds. The vials contain full-length Thymosin Beta-4, a 43-amino-acid peptide (CAS 77591-33-4). The capsules contain the 7-amino-acid Ac-LKKTETQ fragment (CAS 885340-08-9). Both include the LKKTET actin-binding motif, but they differ in size, structure and format, so researchers should choose based on which compound their study requires.

Does the capsule format of TB-500 change its mechanism of action compared to vial preparations?

No. The core mechanism involving G-actin interaction through the LKKTET motif is intrinsic to the TB-500 molecule and remains unchanged regardless of formulation format. Experimental differences between formats relate to formulation characteristics rather than the underlying molecular mechanism. This makes the capsule format useful for comparative investigations of actin-regulatory pathways, peptide-associated signaling processes, and formulation-dependent experimental variables.

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