Product Usage: This product is intended for research purposes only.
All product information available on this website is for educational purposes only. Any form of bodily introduction into humans or animals is strictly prohibited by law. This product should only be handled by licensed and qualified professionals. It is not a drug, food, or cosmetic, and must not be misbranded, misused, or mislabeled as such.
Thymosin Alpha 1
During our packaging transition, you may receive products with either our previous or updated label. Rest assured, the formulation, purity and quality remain exactly same as standards.
Thymosin Alpha 1 (Tα1) is a synthetic peptide fragment derived from prothymosin alpha, known for its role in intracellular signaling and peptide-mediated regulatory pathways. It interacts with toll-like receptors (TLRs) and major histocompatibility complex (MHC) molecules, modulating molecular signaling cascades.
This peptide undergoes proteolytic degradation, with primary metabolism occurring via enzymatic hydrolysis and renal clearance.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C129H215N33O55 |
|---|---|
| Synonyms | Thymalfasin, Tα1 |
| Molar Mass | 3,108.26 g/mol |
| CAS Number | 62304-98-7 |
| PubChem CID | 16130571 |
| Total Compound Content | 5 mg per vial |
| Shelf Life | 36 months |
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
What is the mechanism by which Thymosin Alpha-1 interacts with innate immune signaling pathways?
Thymosin Alpha-1 has been extensively investigated for its interactions with Toll-like receptor-associated signaling networks, particularly TLR9- and TLR2-dependent pathways. Experimental studies have demonstrated activation of MyD88-dependent signaling cascades, resulting in modulation of downstream transcriptional regulators including NF-κB. These signaling interactions make Tα1 a valuable research tool for investigating pattern-recognition receptor pharmacology, innate immune signaling mechanisms, and coordinated immune regulatory networks.
How does Thymosin Alpha-1 differ from Thymosin Beta-4 (TB-500) in research applications?
Thymosin Alpha-1 and Thymosin Beta-4 are structurally distinct thymic-derived peptides with different molecular targets and signaling pathways. Thymosin Alpha-1 is primarily investigated for its interactions with innate immune signaling networks, Toll-like receptor pathways, and immunomodulatory mechanisms. Thymosin Beta-4 is characterized by its interaction with actin-associated regulatory systems and cytoskeletal signaling pathways. As a result, the two peptides are utilized in distinct areas of peptide pharmacology and mechanistic research.
What are the primary research applications of Thymosin Alpha-1?
Thymosin Alpha-1 is widely used in studies of Toll-like receptor signaling, innate immune pathway regulation, dendritic cell-associated signaling mechanisms, cytokine regulatory networks, and peptide-mediated immune communication systems. Experimental investigations have examined its role in pattern-recognition receptor pharmacology, immune signaling pathway modulation, and coordinated interactions between innate and adaptive immune regulatory processes. These characteristics make Tα1 a valuable tool for mechanistic studies of immunomodulatory peptide pharmacology.
-
-
SALE
-
-
-
-
