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L-Theanine – Powder, 100 grams
During our packaging transition, you may receive products with either our previous or updated label. Rest assured, the formulation, purity and quality remain exactly same as standards.
L-Theanine (γ-glutamylethylamide) is a naturally occurring non-protein amino acid investigated for its effects on glutamatergic, GABAergic, and monoaminergic signaling pathways. Experimental studies have demonstrated interactions with glutamate receptor systems, including NMDA and AMPA receptor-associated signaling mechanisms, as well as modulation of glutamate transporter activity. Research has also examined its influence on GABA-related neurotransmission, intracellular signaling cascades, and neurotransmitter regulatory networks. Its well-characterized activity profile makes L-Theanine a valuable research tool for investigations of glutamatergic signaling, receptor pharmacology, neurotransmitter modulation, electrophysiological activity, signal transduction mechanisms, and comparative amino acid neuropharmacology.
- High Purity – 99% Purity Guaranteed
- Independently Lab Tested
- Research Grade Quality
- For Laboratory Research Use Only
3D Molecular Structure
Drag to rotate · scroll to zoom| Chemical Formula | C7H14N2O3 |
|---|---|
| Synonyms | γ-Glutamylethylamide, L-γ-Glutamylethylamide, Suntheanine |
| Molar Mass | 174.20 g/mol |
| CAS Number | 3081-61-6 |
| PubChem CID | 439378 |
| Total Compound Content | 100 g powder |
| Shelf Life | 36 months |
Every batch is independently lab tested for identity, purity and potency. View our lab testing program →
How does L-theanine modulate glutamatergic signaling despite structural similarity to glutamate?
L-theanine (γ-glutamylethylamide) is structurally related to glutamate, but its ethylamide substitution alters its interactions with glutamate receptor systems and transport mechanisms. Experimental investigations have demonstrated activity at NMDA receptor-associated signaling pathways, where L-theanine functions differently from glutamate despite structural similarity. Studies have also reported modulation of AMPA receptor-associated processes and interactions with excitatory amino acid transporters (EAATs), making L-theanine a useful research tool for examining receptor-ligand specificity, glutamatergic signaling regulation, and amino acid structure-activity relationships.
What is the basis for using L-theanine in electrophysiological research?
L-theanine has been extensively investigated in studies examining electrophysiological activity patterns and neurotransmitter-associated signaling networks. Experimental research has reported effects on oscillatory neural activity, glutamatergic signaling, GABA-associated pathways, and monoaminergic neurotransmitter systems. These characteristics have made L-theanine a valuable tool for investigations of electrophysiological regulation, neurotransmitter network dynamics, receptor-transporter interactions, and signal integration across multiple neurotransmitter systems.
What solvent systems are commonly used for L-theanine in in vitro research applications?
L-theanine is highly water-soluble and is typically prepared in aqueous buffers, phosphate-buffered saline (PBS), or assay-specific media for biochemical and cell-based experiments. Its favorable aqueous solubility facilitates preparation of defined-concentration stock solutions for receptor pharmacology studies, transporter investigations, concentration-response experiments, and other in vitro applications. The compound's stability and solubility characteristics make it particularly suitable for high-throughput experimental workflows and analytical research programs.
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