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YK-11 (5mg/capsule), 60 Capsules

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Original price was: $111.95.Current price is: $79.95.
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YK-11 is a synthetic steroidal compound that functions as a gene-selective partial agonist of the androgen receptor (AR). Experimental investigations have reported interactions with androgen receptor-mediated transcriptional regulation together with modulation of follistatin (FST)-associated gene expression pathways. Follistatin is a regulatory glycoprotein involved in activin-associated signaling networks and transcriptional control processes, making YK-11 a useful research tool for examining AR-dependent gene regulation and downstream signaling mechanisms.

Research applications include androgen receptor pharmacology, AR partial agonism studies, follistatin-associated pathway investigation, transcriptional regulation research, structure-activity relationship analysis, and mechanistic comparison of steroidal and non-steroidal androgen receptor modulators.

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3D Molecular Structure

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Chemical Formula C25H34O6
Synonyms Myostine, (17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester
Molar Mass 430.54 g/mol
CAS Number 1370003-76-1
PubChem CID 119058028
Total Compound Content 300 mg (5 mg per capsule)
Shelf Life 36 months
YK-11 is a synthetic steroidal compound structurally derived from the androstane scaffold and classified as a steroidal selective androgen receptor modulator (SARM). Unlike full androgen receptor agonists, YK-11 functions as a gene-selective partial agonist of the androgen receptor (AR), producing a distinct receptor-mediated transcriptional profile through differential regulation of AR-dependent gene expression pathways. Experimental investigations have reported modulation of follistatin (FST)-associated transcriptional networks, a characteristic that distinguishes YK-11 from many other androgen receptor modulators. Follistatin is a regulatory glycoprotein involved in activin-associated signaling systems and transcriptional control processes. The combination of AR partial agonism and follistatin-associated pathway modulation has established YK-11 as a valuable research tool for investigating androgen receptor pharmacology, transcriptional regulation, receptor-mediated signaling mechanisms, structure-activity relationships, and mechanistic differences between steroidal and non-steroidal androgen receptor modulators. Supplied in 5 mg capsules. Independently third-party HPLC-tested; COA available per batch.

Every batch is independently lab tested for identity, purity and potency. View our lab testing program →

What distinguishes YK-11 from other androgen receptor modulators?

YK-11 is notable for its gene-selective partial agonism at the androgen receptor (AR) together with reported modulation of follistatin (FST)-associated transcriptional pathways. This combination of receptor-mediated signaling and follistatin-associated gene regulation differentiates YK-11 from many other androgen receptor modulators and has made it a valuable research tool for investigating AR-dependent transcriptional mechanisms, regulatory signaling networks, and pathway-specific gene expression processes.

Is YK-11 a steroidal or non-steroidal androgen receptor modulator?

YK-11 is classified as a steroidal androgen receptor modulator and is structurally derived from the androstane scaffold. This steroidal framework distinguishes it from non-steroidal androgen receptor modulators that utilize alternative chemical architectures. The structural differences between steroidal and non-steroidal compounds make YK-11 useful for structure-activity relationship investigations examining receptor binding characteristics, co-regulator interactions, transcriptional responses, and androgen receptor pharmacology.

Why is follistatin-associated signaling relevant in YK-11 research?

Follistatin (FST) is a regulatory glycoprotein involved in activin-associated signaling systems and transcriptional control processes. Experimental investigations involving YK-11 have examined relationships between androgen receptor activation, follistatin-associated regulatory pathways, and downstream gene expression mechanisms. These characteristics have established YK-11 as a useful research tool for studies of AR-mediated signaling, transcriptional regulation, and the molecular interactions linking androgen receptor activity with follistatin-associated pathways.

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