Mechanism of action of SR9011
To understand the mechanism of action of SR9011, it is necessary to mention the specific nuclear receptor Rev-Erb. This intracellular receptor is a protein molecule that is located in the nucleus and is involved in the regulation of the circadian rhythm of gene expression that affects many biochemical processes. Among the processes "dependent" on Rev-Erb are energy, carbohydrate and fat metabolism.
It is known that the intensity of physiological processes changes during the day. Metabolism accelerates during the day and slows down in the evening, reaching its minimum values late at night. Circadian rhythms of activity, which are often called circadian, are regulated by many mechanisms, including nuclear receptors. One of these regulators is Rev-Erb.
Activation of Rev-Erb leads to the expression of genes that encode proteins of enzyme systems involved in metabolic processes. Under natural conditions, the activity of Rev-Erb increases during the day and decreases at night, which is manifested by the changes in the basal metabolic rate mentioned above.
SR9011 is a selective Rev-Erb modulator. As an agonist (stimulator) of this nuclear receptor, SR9011 promotes the activation of genes that affect the rate of metabolic processes, regardless of the time of day. Taking SR9011 capsules is accompanied by an increase in the rate of energy, lipid and carbohydrate metabolism. The indicators of the basic metabolism increase, the breakdown of fatty acids and glucose in the reactions of aerobic synthesis of ATP is accelerated.
SR9011: Effects and Tissue Specificity
According to lab research the SR9011 modulator is selective and acts selectively on certain tissues. In particular, the drug activates Rev-Erb receptors in the hypothalamus, liver cells, adipocytes, and skeletal muscles. Due to this specificity, it contributes to the improvement of athletic performance and the speedy achievement of the set goals, especially if these include fat burning, weight loss and drawing muscle relief.
Activation of the nuclear receptor Rev-Erb in adipose tissue slows down synthesis and accelerates the breakdown of triglycerides. Free fatty acids formed from triglycerides enter the bloodstream, reach the muscles and are utilized in the aerobic pathway of ATP synthesis.
In muscle tissue, the number of mitochondria increases, and the rate of glucose and fat oxidation increases. In combination with the changes in lipid metabolism described above, this contributes to the most efficient fat burning. The lipolytic effect manifests itself at any initial percentage of fat: the result will be obtained by both people who just want to lose weight and professional athletes who are preparing for a competition.
In the liver, the synthesis of lipids, cholesterol and fatty acids slows down. This has a beneficial effect not only on sports results, but also on the general condition of the body. While taking SR9011 tablets, the level of triglycerides, total cholesterol and low-density lipoproteins (LDL, or "bad" cholesterol) decreases in the blood. The indicators of the lipid profile are improved. Due to the intensification of carbohydrate metabolism, blood glucose and insulin levels decrease.
Study has shown the main effects of the SR9011:
- Increased calorie expenditure;
- Increase of energy reserves in muscles;
- Improvement of fat metabolism, normalization of blood lipid profile;
- Reducing blood sugar, improving carbohydrate metabolism.
SR9011 advantages
Compound not approved by the FDA. Selective modulator SR9011 is a catalyst for fat, carbohydrate and energy metabolism. A safe catalyst that does not interfere with the work of the endocrine system, does not affect the synthesis of hormones of the adrenal glands, thyroid and pancreas, does not disrupt the natural course of metabolic processes.
SR9011 increases the metabolic rate by activating the mechanisms provided by nature itself. Simply put, a person with an initially "slow" metabolism can get the metabolism of a genetically gifted athlete, but without hormonal drugs, without steroids, without central stimulants that deplete the nervous system.
Application of SR9011 in sports
In sports and recreational fitness, the SR9011 is used in workout cycles that focus on weight loss and fat burning. If you are just starting the journey to transforming your body, the SR9011 will help you get your first results quickly, gain confidence and find additional motivation to move forward. In addition, it will give you the right to small errors in your diet, which will go away without a trace thanks to the accelerated metabolism. Please take your doctor advice before taking any dosage.
Professional athletes take SR9011 during periods when they need to dry out, remove subcutaneous fat accumulated during periods of intense mass gain, and achieve maximum relief detail. The SR9011 greatly simplifies competition routing and allows you to approach the stage in perfect shape, even if there were obstacles in the way of unplanned cheat meals and refeeds.
In basic cycles, the SR9011 can be used as an auxiliary tool. It will help minimize the "side effect" of mass gain in the form of increased body fat. The intensification of energy metabolism will give strength for hard strength training. The tolerance to aerobic and anaerobic loads will improve, the training volume will increase, you will be able to train more often, for longer, and with greater efficiency.
Application of SR9011 in sports:
- Weight loss, reduction and subsequent control of body weight;
- Improving the composition of fabrics;
- Drying, drawing and detailing of muscle relief;
- Preparation for the competition;
- Basic cycles (to increase endurance, training volume, duration and intensity of training).
Impact of SR9011 on health
The FDA, that is. Even though SR9011 is not FDA-approved for human use, bodybuilders have been using it to drastically increase their fat loss. But changes in key indicators of carbohydrate and lipid metabolism make SR9011 promising for health purposes. Lowering blood sugar, total cholesterol, triglycerides and LDL cholesterol reduces the risk of developing the following diseases:
- Atherosclerosis;
- Arterial hypertension;
- Metabolic syndrome;
- Obesity;
- Diabetes mellitus type 2;
- Coronary heart disease;
- Stroke, heart attack.
How to take SR9011?
Study have shown while there is no FDA established dosage to get the best results with SR9011, most veterans recommend 1-2 capsules per day. It is advisable to divide the daily dose into 2 doses. The duration of the course is from 8 to 12 weeks.
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