Description
Sildenafil is a phosphodiesterase (PDE5) inhibitor that leads to an increase in the cGMP levels in the smooth muscle cells lining the blood vessels. This action relaxes blood vessels and allows more blood flow.
New research shows that Sildenafil and other PDE-5 inhibitor treatment for erectile dysfunction is linked to a significant reduction in the risk of major adverse cardiovascular events and death in healthy men.