Historical reference
Clomid was first used as a fertility drug in the early 1970s in the United States. Now this drug is widely known outside the United States. Now it is produced under the names: Clomid, Serofen, Sepafar, Omifin, Pergotheim, Gonafen, Duinum, Clostil, Ovamit, Clomifene, Clomiphene and Clostilbegite.
Pharmacological action (according to the manufacturer)
Antiestrogenic. Binds estrogen receptors in the hypothalamus and ovaries. Ingestion is well absorbed from the gastrointestinal tract. Metabolized in the liver. It is excreted in the bile, undergoes enterohepatic recirculation. It is excreted from the body with feces. The half-life is 5-7 days. In small doses, it enhances the secretion of gonadotropic hormones (prolactin, FSH and LH), stimulates ovulation. With a low content of endogenous estrogens in the body, it has a moderate estrogenic effect, with a high level - antiestrogenic. By reducing the level of circulating estrogen, it promotes the secretion of gonadotropins. In large doses, it inhibits the secretion of gonadotropins. Does not possess gestagenic and androgenic activity.
Clomiphene citrate properties
Study have shown when used in men, Clomid (Clomifene, Clomiphene) Tablets acts partly as an antiestrogen and can be used to counteract some of the side effects of anabolic agents such as gynecomastia and water retention. Clomid capsules can also increase the production of follicle-stimulating and luteinizing hormones, which increases testosterone levels. This is especially useful after a "cycle" when endogenous testosterone levels are very low. In this case, Clomid is used together with chorionic gonadotropin and tamoxifen to accelerate recovery after a course. If testosterone is not returned to normal levels within a short time, then serious loss of mass and strength is possible. This is a consequence of the fact that without testosterone / other androgens, the catabolic hormone cortisol becomes the dominant player in the synthesis of proteins in the muscles, causing catabolism, which can eat a significant part of the muscles acquired on the course. It should be noted that all triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to have an estrogen-like effect in the liver. This means that they can block estrogen in some areas of the body, while they can act like estrogen in other areas. An important role here is played by the ability to regulate the level of synthesis of good and bad cholesterol.
When using anabolic steroids, risk factors for the cardiovascular system appear, which are aggravated by the use of aromatase inhibitors. Using Clomid pills, nasal spray and injectable can stop gynecomastia and at the same time maintain the necessary balance of good and bad cholesterol. that all triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to have an estrogen-like effect in the liver. This means that they can block estrogen in some areas of the body, while they can act like estrogen in other areas. An important role here is played by the ability to regulate the level of synthesis of good and bad cholesterol. When using anabolic steroids, risk factors for the cardiovascular system appear, which are aggravated by the use of aromatase inhibitors. Using Clomid (Clomifene, Clomiphene) capsules can stop gynecomastia and at the same time maintain the necessary balance of good and bad cholesterol. that all triphenylethylene compounds (toremifene citrate, tamoxifen citrate, clomiphene citrate) tend to have an estrogen-like effect in the liver.
This means that they can block estrogen in some areas of the body, while they can act like estrogen in other areas. An important role here is played by the ability to regulate the level of synthesis of good and bad cholesterol. When using anabolic steroids, risk factors for the cardiovascular system appear, which are aggravated by the use of aromatase inhibitors. The use of clomid can stop gynecomastia and at the same time maintain the necessary balance of good and bad cholesterol. that they can block estrogen in some areas of the body, while they can work like estrogen in other areas. An important role here is played by the ability to regulate the level of synthesis of good and bad cholesterol. When using anabolic steroids, risk factors for the cardiovascular system appear, which are aggravated by the use of aromatase inhibitors.
The use of clomid (Clomifene, Clomiphene) can stop gynecomastia and at the same time maintain the necessary balance of good and bad cholesterol. that they can block estrogen in some areas of the body, while they can work like estrogen in other areas. An important role here is played by the ability to regulate the level of synthesis of good and bad cholesterol. When using anabolic steroids, risk factors for the cardiovascular system appear, which are aggravated by the use of aromatase inhibitors. The use of clomid can stop gynecomastia and at the same time maintain the necessary balance of good and bad cholesterol.
The drug also stops the negative feedback relationship of estrogens along the hypothalamus-pituitary-testes axis, thereby increasing the production of gonadotropins (LH and FSH). In this action, it is similar to tamoxifen and cyclophenyl. More LH means more testosterone. This effect is most valuable after the "course", within the framework of the comprehensive PCT program. You will take your dosage of Clomid on the day your doctor has advised.
The use of clomiphene citrate (According to the Centres for Disease Control and Prevention Trusted Source)
Reception (for men):
In athletes, it is used at a dosage tables pills of 50-100-150mg per day (depending on the PCT regimen) for 30 days after the "course", in order to bring the testosterone level to normal. As a rule, here it is part of a multi-component recovery scheme.
Reception (for women):
Clomid capsules are commonly used in a complex protocol to treat ovulation disorder. In the case of athletic use in women, Clomid (Clomifene, Clomiphene) is used to reduce the amount of fat on the thighs and to improve the overall appearance of the muscles.
Side effects of clomiphene citrate
Usually, clomiphene citrate is well tolerated, but there are side effects: headache, dizziness, depression, fatigue, anxiety, insomnia, visual impairment; nausea, vomiting; cystic ovarian enlargement, dysmenorrhea, pollakiuria, polyuria, multiple pregnancy; hot flashes, weight gain, pain in the lower abdomen, chest, testicles (in men), hyperthermia, reversible hair loss, allergic skin reactions.
Indications for medicinal use
Anovulatory infertility, dysfunctional uterine bleeding, amenorrhea (dysgonadotropic form, secondary, postcontraceptive), galactorrhea (against the background of a pituitary tumor), polycystic ovaries (Stein-Leventhal syndrome), Chiari-Frommel syndrome, androgenic insufficiency, oligospermia, for the diagnosis of gonadophageal disorders.
1. What is Clomiphene used for?
A: Clomiphene is primarily used as an ovary stimulant, and treats infertility in women. It can also boost testosterone in males without anabolic side-effects.
2. Is Clomiphene the same as Clomid?
A: Yes, Clomiphene, and Clomid are the same. These names are often used interchangeably.
3. Why is Clomiphene banned?
A: Clomiphene has been banned in certain countries as it has not been cleared by their domestic laws and regulations.
4. When should I take Clomiphene tablets?
A: Take Clomiphene tablets according to the dosage and timings suggested by your doctor.
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